Numerous experiments in buffalo breeding have been made, and the subject is far from being a new one. As early as 1701 the Huguenot settlers at Manikintown, on the James River, a few miles above Richmond, began to domesticate buffaloes. It is also a matter of historical record that in 1786, or thereabouts, buffaloes were domesticated and bred in captivity in Virginia, and Albert Gallatin states that in some of the northwestern counties the mixed breed was quite common. In 1815 a series of elaborate and valuable experiments in cross-breeding the buffalo and domestic cattle was begun by Mr. Robert Wickliffe, of Lexington, Ky., and continued by him for upwards of thirty years.[49] [Note 49: For a full account of Mr. Wickliffe's experiments, written by himself, see Audubon and Bachman's "Quadrupeds of North America," vol. ii, pp. 52-54.] Quite recently the buffalo-breeding operations of Mr. S. L. Bedson, of Stony Mountain, Manitoba, and Mr. C. J. Jones, of Garden City, Kans., have attracted much attention, particularly for the reason that the efforts of both these gentlemen have been directed toward the practical improvement of the present breeds of range cattle. For this reason the importance of the work in which they are engaged can hardly be overestimated, and the results already obtained by Mr. Bedson, whose experiments antedate those of Mr. Jones by several years, are of the greatest interest to western cattle-growers. Indeed, unless the stock of pure-blood buffaloes now remaining proves insufficient for the purpose, I fully believe that we will gradually see a great change wrought in the character of western cattle by the introduction of a strain of buffalo blood. The experiments which have been made thus far prove conclusively that-- (1) The male bison crosses readily with the opposite sex of domestic cattle, but a buffalo cow has never been known to produce a half-breed calf. (2) The domestic cow produces a half-breed calf successfully. (3) The progeny of the two species is fertile to any extent, yielding half-breeds, quarter, three-quarter breeds, and so on. (4) The bison breeds in captivity with perfect regularity and success.