The cause of the disease has not been satisfactorily determined, but it is definitely known that the virus which reproduces the disease comes from the ulcers and natural secretions and excretions of the body, such as milk, saliva, perspiration, feces, urine, and exhalation. The contagion is not harmful when dried. Infected animals lose the power of transmitting the disease when the ulcers of the mouth, feet, and udder have healed. In from three to five days after infection the animal has a moderate fever. The appetite is lost and the mouth is kept closed. There is a dribbling of saliva, and in two or three days yellowish-white spots the size of a hemp seed appear on the gums, the lower surface of the tongue, lining of the mouth and on the lips. These eventually attain the size of a silver dollar. They run together, burst and form painful, foul-smelling ulcers. At this stage the saliva is more profuse and ropy and the animal makes characteristic smacking noises with the mouth. Infected animals lose flesh rapidly, in some cases as much as 100 pounds in eight or ten days. The milk is thick, yellowish-white, has a bad taste, and is with difficulty made into cheese or butter. The reduction in milk yield during the sickness and for some time after recovery is 50 to 75 per cent. Usually, a short time after an appearance of the disease in the mouth parts, there is a redness, heat and swelling of the skin at its junction with the hoof and especially between the toes and upon the soles of the foot. Similar ulcers to those on the mouth appear on the feet and soon burst. The animal becomes lame and moves stiffly and lies down a great deal. These ulcers ordinarily heal up in one or two weeks. In some cases the animal dies suddenly, in others lingers a few hours with difficult breathing and discharge of blood from the nose, and finally dies of paralysis of the heart and lungs. In still other cases emaciation and reduction of milk flow is the only bad result. Sometimes ulcers form at the root of the horn and cause the horn to drop off. Owing to the nature of the disease, its contagion and danger, treatment should be in line of prevention and in destruction of infected animals. While the disease yields to treatment, our best suggestions when the disease is suspected is in notification to the state officers and in securing the services of a veterinarian who will be able to advise what is best to do. [Illustration: FOOT ROT A disease usually associated with sheep. It is sometimes so serious that the entire hoof rots away.] =FOOT PUNCTURE.=--See Wounds and Their Treatment.