=GLANDERS.=--A contagious disease peculiar to the horse, ass, and mule, and may be communicated to human beings, and also sometimes to carnivorous animals in menageries, by means of infected horse flesh, and also by means of inoculation to field mice, guinea pigs, dogs, cats, goats, rabbits, and sheep. Pigs are not readily susceptible and cattle appear to be immune. Like all diseases of a contagious or infectious character, glanders is due to a specific organism, known as the bacillus malleus. The external manifestations of glanders differ and consequently the disease is spoken of as glanders or farcy, depending upon the symptoms presented. The disease is known as glanders when the horse suffering from it has a discharge from the nose, ulcers on the septum nasi (the partition dividing the nasal cavities) and enlarged submaxillary glands, and is known as farcy when the affected animal has farcy “buds” or ulcers on the skin, and corded lymphatic vessels running from one “bud” to another. In farcy, the corded lymphatics, “buds” and ulcers on the skin are very apt to be on the inside of one hind leg or the other, but may appear on the inside of a fore leg, or on the neck or body. Farcy was, in olden times, thought to be a different disease from glanders, and was believed by many to be curable, while glanders has always been generally believed to be incurable, but it is now known that farcy is simply one manifestation of glanders. It has been found that a horse with glanders may give another farcy, and vice versa. Guinea pigs inoculated with the discharge from a glandered horse’s nose will develop glanders, and pure cultures of the glanders bacillus can be obtained from them, and in a similar way if guinea pigs are inoculated with the discharge from a sore on a horse with farcy glanders may be produced in these little experimental animals, and upon post mortem examination pure cultures of the glanders bacillus can be obtained from the lesions of the disease produced in them. Glanders and farcy may again be divided into two forms, acute and chronic glanders, and acute and chronic farcy. In the acute form the disease develops rapidly, the lesions form more speedily and with greater rapidity than in the chronic form and the animal loses strength and condition and dies within the course of a few weeks, sometimes in the course of a week or two. It is not unusual to meet with an animal showing symptoms of both glanders and farcy, especially in the acute form.