Dr. Kellogg's argument is a very plausible one; for many years it sufficed to keep me from trying the experiment of the fast. I know that it has kept many other people. His claim is, in brief, that during the fast the body is living off its own tissue; that we are therefore meat-eaters, and even cannibals, while fasting. We are living on a kind of food which is over-rich in proteid, and which generates excessive quantities of uric acid, indican, etc. This, as I say, sounds plausible, but I found by actual experiment that the facts do not work out according to the theory. I myself have taken a week's fast recently, with perfect success. During this time I had not one particle of weakness or trouble of any sort. Perhaps it may be that my body was excreting undue amounts of uric acid and indican, but I did not know it, and it did me no harm so far as I could discover. I am much less afraid of the consequences of living from my own body tissue, since I have tried for myself the experiment of living on the tissues of other animals. I am trying to get at the truth about these questions, and I know that you are trying to do it also. For three years I did myself incalculable harm by accepting blindly statements that meat was the prime cause of autointoxication, together with other high proteid food. I lived on starches and sugars, grew pale and thin and chilly, and, as I was accustomed to phrase it, was never more than fifteen minutes ahead of a headache. I can give myself a headache at any time at present by two or three days of eating rice, potatoes, white flour, and sugar. Apparently I cannot give it to myself by eating any possible quantity of broiled lean beef. So far as I can make out, beef is the one article of diet which never does me any harm, no matter how much of it I eat. The same thing is true, apparently, with my little boy. I wish you would tell me what you think about all this. I wish that I could induce you to try the experiment of fasting again with the use of the enema and the copious water drinking. Still more do I wish that you could be induced to try it with some people who need it--some people who are desperately ill, and who have not been able to get well by following the low proteid diet. Sincerely, UPTON SINCLAIR. NORWICH, CONN., U. S. A. Dec. 23, 1910. MY DEAR MR. SINCLAIR,--Your valued favor of the 14th inst. received enclosing copy of your letter to Horace Fletcher. I have read your letter to Mr. Fletcher with much interest, and I have also read Mr. Fletcher's letter to Dr. Kellogg in _Good Health_.