In the next stage a soft warty excrescence, which is the matrix of the sore, pushes its way through the true skin by forcing it aside rather than breaking down its substance. On reaching the surface the granulations which form this out-growth exude a fluid which is highly contagious. It forms in time a crust or scab, the reddish appearance of which is very characteristic of the yaws eruption. If this be removed by means of oil or a poultice, the granulated surface of the sore beneath it has that resemblance to a raspberry or mulberry which has given the name of _Framboesia_ to the disease. In some cases the crust assumes a curvilinear outline, recalling the appearance of the well-known Pharaoh's serpent. These are especially seen about the corners of the mouth, the neck and the axillæ, and constitute the _thoko ndina_ or true yaws. In other cases they retain a circular shape on all parts of the body, and are then called _thoko mbulewa_ or button or limpet yaws. During the healing process they become converted into annular or horse-shoe patterns, the centre receding before the periphery. The sores may remain for two weeks or they may persist for fully two years. Throughout the progress of the case they may number anything from one to several hundred. The commonest number is from six to twenty or thirty. Weakly and ill-nourished children take the disease more easily than strong ones. While the active symptoms seldom last for more than two months, the dormant features last much longer, and some of the tertiary consequences may appear at almost any age. The chief ill effects from _thoko_ are dysentery, diarrhoea, and marasmus; sometimes the joints are implicated, even the larger ones, such as the wrists, knees and ankles, and partial paralysis may follow; pot-belly is a frequent concomitant, and _tabes mesenterica_ are believed to follow it. In a later period of life the feet of those who have had yaws as children become affected by the disease, and on account of the thick and horny skin by which the soles of shoeless races are protected the extrusion of the growing yaw through the sole becomes an acutely painful process. Not only do the typical granulations known as _suthuvi_ and _soki_ force their way through the skin, but the sole is also liable to a cracking and peeling form of excoriation called _kakatha_, which is nearly as painful and is also said to be contagious. The Fijians do not recognize the connection between any of the sequelæ of yaws and the original disease, and hence perhaps the indifference with which they regard it. [Pageheader: MODE OF INOCULATION]