Why should this general evidence count for less than the few experimental cases upon which the mosquito theory is built up? These latter are mostly conspicuous by their weakness. Take, for example, the mosquito-proof hut placed at Ostia, and inhabited for three months by Dr. Sambon, Dr. Low, Mr. Terzi, and their servants. What analogy does this well-ventilated erection, raised above the soil, bear to many of the insanitary homesteads of the Campagna? What analogy is there between its healthy inhabitants, further fortified by zest for a theory in dire need of proof, and the permanent dwellers in those unpropitious surroundings? If we admit strength in the case of the infected mosquitoes sent to the London Tropical School, whose stings are said to have produced attacks of fever in the late Dr. Thurburn Manson and Mr. George Warren, we must also remember that Abele Sola in the Santo Spirito Hospital in Rome, according to the account quoted by Herms in his _Malaria: Cause and Control_, is claimed to have fallen a victim to this disease from the bites of mosquitoes that had developed from larvæ in his own room, and therefore could not be reckoned as infected. Moreover, they numbered hardly any Anophelines, and of the very few present, it was not known whether any stung the patient. Yet, according to the modern theory, Anophelines alone could have been responsible for the mischief. The proverbial grain of salt seems a necessary condiment for the cases of experimenters. In the short space at our disposal, we are not concerning ourselves with the micro-organism, first discovered in Algiers by Dr. Laveran, and considered to be the parasite of malaria. Without in the least committing oneself to a general belief in the germ-theory of disease, there may, here and there, be maladies produced by parasites. Yet, apparently, fever, bearing all the clinical symptoms of malaria, may occur without the presence in the blood of such organisms, no matter whether parasitic or inbred. On page 8 of the Medical Report of the Federated Malay States’ Government reference is made to an unusual swarm of sandflies, and the following commentary is given. “Whether sandfly fever exists we are not prepared to say, but many cases _with all the clinical symptoms_ were noted and _no malarial parasite was detected_ on blood examination.” Hence the sandflies come under suspicion! Might not another moral be drawn, and that is that fever may be due to causes less crude than the inoculation of parasites by objectionable insects?