But it was in Pennsylvania that the center of Scotch-Irish power lay. "These bold and indigent strangers, saying as their excuse when challenged for titles that we had solicited for colonists and they had come accordingly,"[104:3] and asserting that "it was against the laws of God and nature that so much land should be idle while so many christians wanted it to work on and to raise their bread," squatted on the vacant lands, especially in the region disputed between Pennsylvania and Maryland, and remained in spite of efforts to drive them off. Finding the Great Valley in the hands of the Germans, they planted their own outposts along the line of the Indian trading path from Lancaster to Bedford; they occupied Cumberland Valley, and before 1760 pressed up the Juniata somewhat beyond the narrows, spreading out along its tributaries, and by 1768 had to be warned off from the Redstone country to avoid Indian trouble. By the time of the Revolution, their settlements made Pittsburgh a center from which was to come a new era in Pennsylvania history. It was the Scotch-Irish and German fur-traders[104:4] whose pack trains pioneered into the Ohio Valley in the days before the French and Indian wars. The messengers between civilization and savagery were such men,[105:1] as the Irish Croghan, and the Germans Conrad Weiser and Christian Post. Like the Germans, the Scotch-Irish passed into the Shenandoah Valley,[105:2] and on to the uplands of the South. In 1738 a delegation of the Philadelphia Presbyterian synod was sent to the Virginia governor and received assurances of security of religious freedom; the same policy was followed by the Carolinas. By 1760 a zone of Scotch-Irish Presbyterian churches extended from the frontiers of New England to the frontiers of South Carolina. This zone combined in part with the German zone, but in general Scotch-Irishmen tended to follow the valleys farther toward the mountains, to be the outer edge of this frontier. Along with this combined frontier stream were English, Welsh and Irish Quakers, and French Huguenots.[105:3]