With the waning of the ovarian function, the thyroid type will also exhibit its particular flare. If there is thyroid excess the woman will be excitable and irritable, the thyroid deficient will be depressed and dull, the thyroid unstable (that is swinging between excess and deficiency) will have a cyclic up and down alternation of mood and temperament. The adrenal centered will have a high blood pressure and masculinoid traits, the adrenal inferior will have a low blood pressure and suffer from a constant weakness and fatigability. So each form of reaction to the critical ages is individualized according to the predominating glandular influence in the constitution of the woman. When the womb has atrophied, and the breasts have shrunk, the typical tan complexion, and the angular masculinoid figure, face and psyche follow, and the transfiguration has been completed. Man has his critical age of sex cell deterioration as well as woman. The age period swings between forty-five and fifty-five. Here enters upon the scene that organ of external and internal secretion, the prostate, the most important of the accessory sex glands in the male. Experiments with its extract upon growing tadpoles have demonstrated it to have the same differentiating effects as thyroid, but without the poisoning effects. Furthermore, the microscope reveals cyclic changes in its cells comparable to the menstrual phenomena of the uterus. Indeed it is accepted as the homologue or male representative of the uterus. Small and undeveloped during childhood, its growth at puberty parallels that of the other reproductive organs. Its secretion has been shown to be necessary to the vitality of the sperm cells. The regression of the prostate, its retirement from the field of sex competition, is the central episode of the male climacteric. Accompanying its shrinking are prominent an irritable weakness, despondency, and melancholia, which may emerge at any time if there is disease or disturbance of it. The influence of the prostate upon man's mental condition, and its contribution to the sex index, still remains to be investigated in detail. SEX CRISES