The excellent bishop Cabezas, who had so signally distinguished himself during the preceding administration, was in the year 1610 promoted to the bishopric of Guatemala. He was replaced by the Carmelite padre Don Alfonso Enriquez de Almendariz, who immediately made efforts to have the king remove his episcopal seat to Havana. This caused serious disputes between the bishop and Governor Pereda, who sent the king a report disapproving of this removal. The conflict between the two culminated in the excommunication of Pereda by the bishop. The administration of his successor, Don Sancho de Alquiza, former governor of Venezuela and Guyana, was brief. He was inaugurated on the seventh of September, 1616, and died on the sixth of June, 1619. He was much interested in the economic development of Cuba, promoted the development of sugar industry, encouraged the employment of negroes on the plantations. His efforts to exploit the mineral wealth of the island were also commendable. He placed the supervision of the copper mines under the direction of the military government and the work proceeded most promisingly. The copper extracted was of superior quality and two thousand quintals of the metal were annually exported to Spain. The sudden death of Alquiza led to much agitation due to the violent spirit of rivalry between the auditor Don Diego Vallizo and the Castellan of the Morro, Geronimo del Quero, who aspired to the governorship. A great calamity occurred in Havana during this interim administration. On the twenty-second of April, 1620, a fire broke out and assumed such disastrous proportions, that two hundred homes were destroyed and the growth of the city was for a time seriously crippled.