"The opium trade," observe the Commissioners, "requires likewise attention. The English in Bengal have assumed an exclusive right to collect the same, and they dispose of a considerable number of chests containing that article annually at Calcutta by public auction. It is much in demand on the Malay coast, at Sumatra, Java, and all the islands towards the east and north, and particularly in China, although the use thereof is confined to the lower classes. The effect which it produces on the constitution is different, and depends on the quantity that is taken, or on other circumstances. If used with moderation, it causes a pleasant, yet always somewhat intoxicating sensation, which absorbs all care and anxiety. If a large quantity is taken, it produces a kind of madness, of which the effects are dreadful, especially when the mind is troubled by jealousy, or inflamed with a desire of vengeance or other violent passions. At all times it leaves a slow poison, which undermines the faculty of the soul and the constitution of the body, and renders a person unfit for all kind of labour and an image of the brute creation. The use of opium is so much more dangerous, because a person who is once addicted to it can never leave it off. To satisfy that inclination, he will sacrifice every thing, his own welfare, the subsistence of his wife and children, and neglect his work. Poverty is the natural consequence, and then it becomes indifferent to him by what means he may content his insatiable desire after opium; so that, at last, he no longer respects either the property or life of his fellow-creature. "If here we were to follow the dictates of our own heart only, and what moral doctrine and humanity prescribe, no law, however severe, could be contrived, which we would not propose, to prevent at least that in future, no subjects of this Republic, or of the Asiatic possessions of the state, should be disgraced by trading in that abominable poison. Yet we consider this as absolutely impracticable at present with respect to those places not subject to the state. Opium is one of the most profitable articles of eastern commerce: as such it is considered by our merchants; and if the navigation to those parts is opened to them (which the interest of the state forcibly urges), it is impossible to oppose trading in the same. In this situation of affairs, therefore, we are rather to advise, that general leave be given to import opium at Malacca, and to allow the exportation from thence to Borneo and all the eastern parts _not_ in the possession of the state."