For some time previous to this period the removal of the medical department of Transylvania University at Lexington to this city had occupied much attention, and had created some bitterness of feeling between the two cities. In this year this vexed question was finally decided by the Legislature against the removal; no less to the gratification of Lexington than to the serious annoyance of this city. The examination of the subject however brought to light an old charter, passed in 1833 and amended in 1835, which sufficed to enable a new school of medicine to be established here. The city accordingly set apart four acres of ground and the sum of $50,000 in money for its use, and so organized a medical school here, of which Messrs. Caldwell, Cooke, Cobb, Flint, Yandell, Miller and Locke were the professors. In February of the next year, the corner stone of the building to be erected by the city for this use was laid, and soon after Dr. Flint, with the money appropriated for that purpose, visited Europe, and purchased a fine library and apparatus for the Institution. Few, if any medical schools in the United States, have ever risen as rapidly in public favor, or as speedily attained as high position in public estimation as this. The first course of lectures was delivered to 80 students, the second to 120, the third to 205, the fifth to 262; and since that time the classes have reached 400 pupils. It has attained the rank of the first school of medicine in the West, and is second to few in the country. There is now another medical school in this city, which will be noticed at the proper place. The next year--1838--brings us to the opening of a railroad to Portland. This road was intended to connect with the Lexington and Ohio railroad. It was kept in employ but a very short time, the citizens on Main Street below the depot at Sixth were violently opposed to the road, and used every effort to impair its usefulness. After the establishment of the Blind Asylum here, the profits of this road were transferred to that institution; but it did not long enjoy the advantages so offered, for the road was discontinued by an application to court from some of the citizens, as offensive to some, and unprofitable to all. A glance at the population of the city for this year will show, that in spite of the commercial difficulties of the time, the city still grew with astonishing rapidity. It had now reached a population of 27,000, showing a gain of 7,033 in three years.