"Louisville is situated on an open plain, where the wind has access from every direction; upon a sandy soil, which readily absorbs the water that falls upon it; susceptible of adequate drainings; supplied bountifully with pure lime stone water, which is filtered through a depth of thirty or forty feet of sand; its streets are wide and laid off at right angles--north and south, east and west--giving the freest ventilation; and the buildings compact, comfortable, and generally so constructed as to be dry and to admit freely the fresh air. It is situated upon the border of the beautiful Ohio, and environed by one of the richest agricultural districts in the world, supplying it with abundance of food, and all the comforts and luxuries of life. It must, under the guidance of science and wise legislation, become, if it is not already, one of the healthiest cities in the world. Its proximity to the rapids of the Ohio may add to its salubrity, and it is certain that the evening breezes wafted over them, produce an exhilarating effect, beyond what is derived from the perpetual music of the roar of the falls." It may be proper to add the following table of the comparative statistics of annual mortality of the resident population as ascertained from official sources. In Louisville the deaths are one to 50. Philadelphia do do 36. New York do do 37. Boston do do 38. Cincinnati do do 35. Naples do do 28. Paris do do 33. London do do 39. Glasgow do do 44.