Until quite lately it was thought that no means of cure, strictly so called, existed. The germs are so minute, and are capable of such diffusion and adherence in a hive, that half-measures proved, as usual, of no avail. The removal of the combs and bees to a fresh hive, and thoroughly sprinkling them with salicilic acid and water, has been recommended as a remedial course; but bee-keepers found that nothing short of the complete destruction of the infected community was likely to be really effective, and the first loss, in such a case, might save the entire destruction of all the stocks in the apiary. The very honey stored in the combs had to be sacrificed also; for in it the dangerous germs settle, and being used by the nurse-bees for feeding the larvæ, become the continued, and possibly unsuspected, source of mischief to any hive to which it is imparted. If the disease appeared in a straw skep, it was considered desirable to destroy it with fire. If it found its way into a bar-frame hive, every frame, every portion, even every crevice, must be treated. Thorough boiling in a copper has been found helpful in eradicating the mischief, but could not alone be relied upon. A strong mixture of chloride of lime and water, or of salicilic acid and water, applied carefully to every part, has been found more effective. The important facts to be remembered are that, owing to the extreme minuteness of the germs, their multitudes, and their great vitality, it is very easy for some to escape destruction, and to become the sources of future mischief, unless the most radical methods of destruction are applied to them.