The disease is, for the most part, obscure, and is best recognized when medicine has become powerless. If early detected, a limited, but sufficient supply of nutritious food; plenty of, but not exhausting labor, with a long course of iodine in alterative doses, are calculated to work some beneficial change. Iodide of potassium Two ounces. Liquor potassæ One quart. Mix, and give two tablespoonfuls night and morning, in a pint of water. Commonly, however, bleeding from the liver is the earliest recognized indication of disease. Then the horse, with depressed head, is found standing before untouched food; often it staggers; sometimes it supports itself against the partition to the stall; it always maintains the erect position with extreme difficulty; the pupil of the eyes are enlarged; if the hand be moved before the sight, the lid does not close; the vision is lost; the pupils are much dilated; the breath, denoting weakness, is short and catching; the jaw is pulseless, and the heart flutters; the visible membranes are deathly; and the bilious nature of the disorder is, in these last parts, apparent. Should the head, only for a minute, be raised, the animal threatens to fall. The first attack is seldom fatal, and possibly might, by proper usage, be recovered from. The bleeding, then, is from the substance of the gland, and does not generally burst Glisson's capsule, or the first and fibrous covering of the liver. Glisson's capsule, however, is, by the pressure of fluid, bulged out. The hemorrhage stretches the peritoneum, which is the second or last envelope; and nature, striving to repair the injury, causes the serous investment to inflame,--to become white, opaque, considerably thicker, and altogether stronger than in its normal condition. [Illustration: THE HEAD OF A HORSE SUFFERING FROM INTERNAL HEMORRHAGE.] [Illustration: THE TEST FOR HEMORRHAGE FROM THE LIVER.] There may be an indefinite number of attacks; or the horse, possibly, may succumb to the first assault. Commonly, there are several fits of the same character. Treatment is generally adopted. A dose of aloes is given, though with what intention the author is not aware. Quiet is enjoined; and styptics, as sugar of lead, alum, etc., are administered; and the horse, commonly, under such treatment, seems to recover. It is, however, difficult to change a fixed habit, or to perceive the reason for an alteration after all danger has disappeared. The gentleman again indulges his inclinations. The coachman, to keep up his horse's flesh, fills the manger; the master very rarely orders the carriage; now he can ride, walking is preferred for his own exercise. Soon, a second fit takes place; this time, Glisson's capsule usually yields; but the thickened peritoneum, although pushed farther out, still resists, and now remains the single stay between human perversity and certain death.