which the terrible efficiency was so thoroughly demonstrated during the second half of the century.[135] In September of that year, moreover, Ochino and Vermigli threw off all disguise and openly embraced Protestantism. This naturally cast suspicion on their admirers and the viceroy commenced a persecution; preachers were set to work to controvert the heretical doctrines; an edict was issued requiring the surrender of heretical books, of which large numbers were collected and solemnly burnt, and a pragmática of October 15, 1544, established a censorship of the press. Finally, Toledo wrote to the emperor that sterner measures were necessary to check the evil and Charles ordered him to introduce the Inquisition as cautiously as possible.[136] It seems to have been recognized as useless to endeavor to establish the Spanish Inquisition and Charles was not as firmly attached to that institution as his grandfather Ferdinand had been, but it was hoped that, by dexterous management, the way might be opened to bring in the papal Holy Office.[137] Towards the end of 1546 Toledo wrote to his brother, the Cardinal of San Sisto, who was one of the six members of the Congregation, expressing his desire to introduce the Inquisition and his dread of the consequences, for the very name was an abomination to all, from the highest to the lowest, and he feared that it might lead to a successful revolution. To encompass the object, it was finally resolved to procure from the pope a commission for an inquisitor against heresy which was prevalent among the clergy, both regular and secular. The required commission was issued, in February, 1547, to the prior and the lector of the Dominican convent of Santa Caterina; Toledo did not personally grant the exequatur for it but caused this to be done by the regents of the _Consiglio Collaterale_, but this precaution and the profound secrecy observed were useless. Rumors spread among the people that orders had been received from the cardinals to proceed against regular and secular clerks; the old animosity against anything but the episcopal Inquisition at once flamed up and deputies were sent to the viceroy to beg him not to grant the exequatur. He assured them that he wondered himself at the fact; he had written to the pope that it was not Charles’s will or intention that the Inquisition should be introduced and that meanwhile he had not granted the exequatur. Little faith was placed in his statements and the general belief was that Paul III was eager to create strife in Naples in order to give the emperor occupation there and check his growing ascendency. It is said that he actually sent two inquisitors but, if so, they never dared to show themselves, for there is no allusion to them in the detailed accounts of the ensuing troubles.