When they awake out of this last sleep the attendant should continually be on his guard, as it is then that diseases break out. The worms suffering from these different diseases have received different names. There are besides the _luisettes_ the _arpians_--that is to say, worms that have exhausted all their energy in the work of the last moult, and have not even strength to eat--the _yellow_, or _fat_ worms, which are swollen, of a yellowish colour, and which very easily die; the _flats_ or _mous_, the soft or indolent ones which, after having eaten a great deal and become very fat, die miserably, and enter into a state of putrefaction. And lastly, it is at this age that the _muscardine_, which hardly shows itself at any other age of the insect, appears with great intensity. The _muscardine_ is a terrible scourge to the rearers of silkworms. The losses which result from this disease in France are estimated at at least one-sixth of the profits. No particular symptom allows of our recognising the existence of this disease in worms which, however, contain its germ; only, the worm, which has eaten up to that time as usual, appears almost in a moment to change to a duller white; its movements become slower, it becomes soft, and is not long before it dies. Seven or eight days after its death it becomes reddish and completely rigid. Twenty four hours afterwards a white efflorescence shows itself round the head and rings, and soon after the whole body becomes floury. This flour is a fungus called _Botrytis bassiana_, of which the _mycelium_ develops itself in the fatty tissue of the caterpillar, attacks the intestines, and fructifies on the exterior. This fungus has been considered as the immediate cause of the _muscardine_, and has been also regarded as the last symptom or end of the disease. The communication of the disease by contagion has alternately been admitted and denied. As its true cause, and any efficacious means of opposing it, are still unknown, the breeders of silkworms must be content to apply--so as to prevent or struggle against this dreadful scourge--the precepts of hygiene: good ventilation, excessive cleanliness, frequent _délitements_, and good food properly prepared. After the _muscardine_, we must mention another epidemic disease still more terrible, the _gattine_. This disease shows itself from the very beginning of the rearing, and increases in intensity at each age, so that the number of worms able to enter regularly into the moult becomes smaller and smaller. We are still in a state of utter ignorance as to the cause of this last affection, which has occasioned, for the last ten years, incalculable losses in the rearing houses, which threatens the silkworm with complete destruction, and which in the meanwhile has ruined the unfortunate countries of the Cévennes, the principal seat of sericulture in France.