He had contracted a cutaneous disease, from the injudicious use of calomel, while a tutor in Yale College; and its effects increased so much now, that his parishioners, who had become quite attached to him, in 1825 induced him to undertake a voyage to Europe. A year's travel, in Great Britain, Germany, France, and other countries, failed to restore his health, and soon after his return to the United States he resigned his charge of the Park-street church, and undertook the Presidency of Hamilton College, which in turn he was compelled to surrender, and in 1830 he opened, at New-Haven, an Academy, in which he was assisted by his wife, a daughter of the late Judge Daggett. The decline of Mrs. Dwight's health, and other circumstances, induced him to relinquish the business of teaching; he visited the Southern States, was during several sessions chaplain to the United States Senate, and, devoting himself to literature, wrote an elaborate memoir of his great-grandfather, Jonathan Edwards, and several works of less importance, one of which was "The Hebrew Wife," written to illustrate the Jewish laws of marriage, and published in New-York in 1836. The death of his wife, and increasing physical infirmities, led him to adopt a habit of the utmost seclusion in New-York, where he passed nearly all the residue of his life. His last appearance in public was in the summer of 1848, when he consented to act with Mr. John R. Bartlett (now the chief of the Mexican Boundary Commission) and the writer of these paragraphs, as an examiner of one of the departments of the Rutgers Female Institute. He died suddenly, while upon a visit to Philadelphia for the purpose of trying the effect of the hydropathic treatment of his disease, on the 30th of September. In the _Home Journal_ of December 14, Mr. Willis says of him:--