Antigonos was appointed by Antipater to conduct the war against Eumenês, and after many fluctuations of fortune at last captured him and put him to death. This happened early in the year 316 B.C. The fortunes of Alexander’s empire were then left at the disposal of five men—Antigonos, Lysimachos, Ptolemy, Seleukos, and Kassander, the son of Antipater, who had died in the year 319 B.C. The ambition and ever-increasing power of Antigonos soon led his colleagues to form a coalition against him, and a long series of hostilities followed. In the end Antigonos and his son Dêmêtrios, surnamed Poliorkêtês, were defeated by the confederates in the battle of Ipsos in 301 B.C. Antigonos fell on the field of battle, and the greater part of his dominions fell to the share of Seleukos, whose cavalry and elephants had been chiefly instrumental in winning the victory. He received as his reward a great part of Asia Minor as well as the whole of Syria from the Euphrates to the Mediterranean. Ptolemy obtained Phoenicia and Hollow Syria, but these provinces afterwards gave rise to frequent wars between succeeding kings of Egypt and Syria. A war in later times broke out between Seleukos and Lysimachos, in which the latter was slain in 281 B.C. His kingdom of Thrace was afterwards merged in that of Macedonia. Thus the empire of Alexander, after a period of incessant wars continued for upwards of forty years, was divided between the powerful monarchs of Macedonia, Egypt, and Syria. [Illustration: FIG. 5.—DIODOTOS.] [Illustration: FIG. 6.—ANTIOCHOS THE GREAT.]