In these voyages to Guinea the English trade had been in exchange for gold, elephants' teeth and pepper. Trading for slaves had scarcely occurred to these early adventurers. Nevertheless, as early as 1562, John Hawkins sailed for Sierra Leone with three vessels, and there captured three hundred Negroes whom he sold to the Spaniards in Hispaniola.[13] The success of this voyage was so great that in 1564 there was fitted out a second slave raiding expedition in which one of the queen's ships, the Jesus, was employed. As before, Hawkins sold his slaves in the West Indies, this time with some difficulty, because the Spanish officials, who were forbidden to have any trade with foreigners, regarded the Englishmen as pirates.[14] Again, in 1567, Hawkins was on his way to Guinea. By playing off one set of natives against another he procured about 450 slaves and once more set out for the Spanish Indies. Although at first the voyage promised to be successful, he was later set upon by a number of Spanish ships and barely escaped with his life and one badly wrecked vessel.[15] Hawkins' voyages to Africa are worthy of note because he was the first Englishman to engage in the slave trade. To be sure, his piratical seizure of free Negroes broke all the rules of honorable dealing long recognized on the African coast. As a result of his actions the natives held all Englishmen in great distrust for a number of years.[16] The unregulated method of carrying on the African trade, pursued up to this time, ceased to a certain extent when Queen Elizabeth granted the first patent of monopoly to the west coast of Africa, May 3, 1588. The charter of 1588 gave to certain merchants of Exeter, London and other places in England for ten years an exclusive trade to that portion of West Africa lying between the Senegal and Gambia rivers. The great slave and gold producing country of the Gold Coast remained open to all traders. It was therefore evident that, instead of continuing the slave raiding projects of Hawkins, the company intended to resume the exchange of English manufactures for African products. According to its charter the company was not required to pay duties in England either on imports or exports.[17] Although nothing is known of the success of this company, the patent was regarded as of sufficient importance for the earl of Nottingham and others to obtain a continuation of the monopoly.[18]