At the age of nineteen she bade adieu to her aged grandparents, and accompanied her father and step-mother to Ohio, in 1794. A year previous to this time, Judge Symmes had located a small colony of settlers who had accompanied him from New Jersey, at a point on the Ohio river, afterward known as North Bend. Returning to the Eastern States, he married Miss Susan Livingston, a daughter of Governor Livingston, of New York, and in the autumn started again, accompanied by his wife and daughter, for his frontier home. The journey was made with great difficulty, and the party did not reach North Bend until the morning of the 1st of January, 1795. Thus was the youthful Anna a pioneer in the land which she lived to see blossoming as the rose under the hands of civilization and material progression. Judge Symmes was one of the Associate Judges of the Supreme Court of the Northwestern Territory, and was often called to attend court in a distant part of the Territory. During the absence of her father on these journeyings, Anna would spend most of her time with an elder sister, who had previously removed to Lexington, Kentucky. It was while on one of these visits to her sister, Mrs. Peyton Short, that she formed the acquaintance of her future husband, then Captain Harrison,[16] of the United States Army, and in command of Fort Washington, the present site of Cincinnati. The youthful Virginian was much attracted by the gentle, modest manners and the sweet face of Anna Symmes, and he determined on winning her hand. The effort was highly successful, for they were married at her father’s house, North Bend, Ohio, November 22d, 1795. Footnote 16: William Henry Harrison, the third and youngest son of Benjamin Harrison, of Virginia, was born the 9th day of February, 1773, at Berkley, on the James river, about twenty-five miles below Richmond, in Charles City county. His father was a signer of the Declaration of Independence, a member of the Continental Congress, and afterward Governor of Virginia. Young Harrison was educated at Hampden Sydney College, and afterward studied medicine. After his father’s death, in 1791, he became the ward of Robert Morris, the celebrated financier, whose private fortune so often relieved the sufferings of the Continental Army. When about to graduate as a physician, the reports of troubles in the West decided him to join the frontier troops. The opposition of his excellent guardian was not sufficient to deter him from his purpose, and as his design was approved by Washington, who had also been a warm friend of his father, he received from that noble warrior an ensign’s commission in the first regiment of United States Artillery, then stationed at Fort Washington.