The most obvious feature, the outstanding element that at once strikes the modern observer in these 'Coan' writings, is the enormous emphasis laid on the actual course of disease. 'It appears to me a most excellent thing', so opens one of the greatest of the Hippocratic works, 'for a physician to cultivate _pronoia_.[60] Foreknowing and foretelling in the presence of the sick the past, present, and future (of their symptoms) and explaining all that the patients are neglecting, he would be believed to understand their condition, so that men would have confidence to entrust themselves to his care.... Thus he would win just respect and be a good physician. By an earlier forecast in each case he would be more able to tend those aright who have a chance of surviving, and by foreseeing and stating who will die, and who will survive, he will escape blame....'[61] [60] This word _pronoia_, as Galen explains (εις το Ἱπποκρατους προγνωστικον {eis to Hippokratous prognôstikon}, K. xviii, B. p. 10), is not used in the philosophic sense, as when we ask whether the universe was made by chance or by _pronoia_, nor is it used quite in the modern sense of _prognosis_, though it includes that too. _Pronoia_ in Hippocrates means knowing things about a patient before you are told them. See E. T. Withington, 'Some Greek medical terms with reference to Luke and Liddell and Scott,' _Proceedings of the Royal Society of Medicine_ (_Section of the History of Medicine_), xiii, p. 124, London, 1920. [61] _Prognostics_ 1. Just as the Cnidians by dividing up diseases according to symptoms over-emphasized diagnosis and over-elaborated treatment, so the Coans laid very great force on prognosis and adopted therefore a largely expectant attitude towards diseases. Both Cnidian and Coan physicians were held together by a common bond which was, historically if not actually, related to temple worship. Physicians leagued together in the name of a god, as were the Asclepiadae, might escape, and did escape, the baser theurgic elements of temple medicine. Of these they were as devoid as a modern Catholic physician might be expected to be free from the absurdities of Lourdes. But the extreme cult of prognosis among the Coans may not improbably be traced back to the medical lore of the temple soothsayers whose divine omens were replaced by indications of a physical nature in the patient himself.[62] We are tempted too to link it with that process of astronomical and astrological prognosis practised in the Mesopotamian civilizations from which Ionia imitated and derived so much. Religion had thus the same relation to medicine that it would have with a modern 'religious' medical man as suggesting the motive and determining the general direction of his practice though without influence on the details and method.