His sickness troubled him grievously, for he had undergone much during his life. He had worked day and night while he was with Laban, and his conflicts with the angel and with Esau, though he came off victor from both, had weakened him, and he was not in a condition to endure the hardships of disease.[358] THE BLESSING OF EPHRAIM AND MANASSEH All the years of Jacob's sojourn in Egypt, Asenath, the wife of Joseph, was his constant nurse. When she saw his end drawing nigh, she spoke to Joseph: "I have heard that one who is blessed by a righteous man is as though he had been blessed by the Shekinah. Therefore, bring thy sons hither, that Jacob give them his blessing."[359] Though Joseph was a devoted and loving son to his father, he was not in constant attendance upon him, because he wanted to avoid giving him the opportunity of inquiring into the circumstances of his coming to Egypt. He was apprehensive that Jacob might curse his sons and bring death upon them, if he discovered the facts connected with their treacherous dealings with Joseph. He took good care therefore never to be alone with his father. But as he desired to be kept informed of his welfare, he arranged a courier service between himself and Jacob. Now when Joseph received the news of his father's having fallen sick, through his messenger, as well as through Ephraim, whom Jacob was instructing in the Torah, he hastened to the land of Goshen, taking his two sons with him. He desired to have certainty upon five points: Would his father bless his two sons, who were born in Egypt, and, if so, would he appoint them to be heads of tribes? Would he assign the rights of the first-born unto himself, and, if so, would he divest Reuben of such rights altogether? And why had his father buried his mother Rachel by the wayside, and not carried her body to the family tomb at Machpelah?[360] Jacob had also entertained doubts on five points, when he was about to emigrate from Canaan to Egypt: He did not know whether his descendants would lose themselves among the people of Egypt; whether he would die there and be buried there; and whether he would be permitted to see Joseph and see the sons of Joseph. God gave him the assurance, saying, "I will go down with thee into Egypt, and I will surely bring thee up again after thy death, and thy descendants also, and Joseph shall put his hand upon thine eyes." When the time approached for the fulfilment of the Divine promise, God appeared unto Jacob, and He said, "I promised to fulfil thy wish, and the time of fulfilment hath come."