I have not had the courage even to write to you, owing to the great distress of mind that I have been suffering under since I arrived at Genoa, where I found letters informing me incidentally, and supposing I was aware of it, of the death of my sister, whom I hoped to see a few days after the letters themselves reached me. The news of her death was addressed to London, and has reached it since I left. I felt strongly inclined to give up my journey, and return to England at once. I could not, however, do so, for reasons I need not trouble you with, and so here I am, very melancholy, and not enjoying this most wonderful place as I otherwise should. I arrived here the night before last, and have, of course, seen little; but I have seen St. Peter’s, and what more could I have seen, or can I hope to see one tenth as magnificent? Lord Shrewsbury is here, and had made arrangements to present me to the Pope before I arrived.... Yours, &c., &c., A. PANIZZI.” At Rome, Dr. Minzi, who was engaged in ascertaining the origin, and devising the remedy for the fever then prevailing there, encountered his friend Panizzi. The latter, during his stay, was perpetually beset by spies. On leaving, he took the precaution of engaging the company of Minzi, and to him he imparted the following directions:—That, were he carried off at the frontier by police agents, he (Minzi) was to write three letters—one to Sir William Temple, at Naples; a second to Lord Holland, also at Naples; and a third to Lord Shrewsbury. As a matter of fact, he was stopped at the Neapolitan frontier; but, after careful examination of the passport, and much unnecessary delay, was allowed to cross. His name, however, appeared in the so-called _Libro Nero_. On his arrival at Naples he proceeded to Lord Holland’s house, at the Palazzo Roccella, where he remained during his sojourn in the place; he now brought all his energies to bear on the acquisition of every possible scrap of information which might further him in his mission. Before long he received help, and this was from Mr. Fagan,[B] who, having been Attaché at Naples since June, 1837, was, indeed, the only person who was able to assist Panizzi. The help received from him was in the shape of a letter of introduction to the Signora Parilli, which must be allowed to tell its own story:— “Dear Mr. Panizzi, I send you word, through a friend of mine that the Signora Parilli expects you to-morrow morning. She does not know who you are, but introduce yourself as the “friend of Fagan.” An aunt of Poerio is a nun, and knows all about him. Yours, &c., &c., GEORGE FAGAN.”