WE are at length, dearest Mary, through the good providence of God, brought about midway up the river on which the city of Philadelphia stands; but, in consequence of the cholera still prevailing there, we shall be obliged to perform a short quarantine of two or three days in a place about twelve miles on this side of it, and after that we may possibly be detained, previous to our passing the Custom House, for a day or two longer. In less than a week, however, from the present time we are hoping to proceed to New York, and thence on our Canada journey. Like the great Apostle we should thank God and take courage. Many have been his tender mercies towards us, and I feel a calm and blessed power to resign all the future into his hands. We have just passed a most beautiful village (Newcastle), built completely in the English style; but everything now is so fresh and novel that we view it with tenfold interest. We are all, thank God, in very good health, and the cholera has considerably abated at New York. I should hope we are running no risk in proceeding in our intended line, and, indeed, no prudence would be any sufficient safeguard, for I hear that it has spread to very many of the surrounding places, and therefore there is no possibility of getting entirely out of its way; but that God, who directed our steps through the United States, will, I am confident, preserve us. I have been reading twice with great attention a small work of Dr. Granville, which has thrown great light upon my mind, both as to the origin, treatment, and prevention of the disease. It was given by Mr. Grant to Arthur, and I consider it quite providential that it was thrown in my way. Philadelphia, August 22.