He was then in the full maturity of his forty-five years. His great intuition, his imagination, which equalled any poet’s, often carried him to a summit whence an immense horizon lay before him; he would then suddenly doubt this imagination, resolutely, with a violent effort, force his mind to start again along the path of experimental method, and, surely and slowly, gathering proofs as he went, he would once more reach his exalted and general ideas. This constant struggle within himself was almost dramatic; the words “Perseverance in Effort,” which he often used in the form of advice to others, or as a programme for his own work, seemed to bring something far away, something infinite before his dreamy eyes. At the end of the year, an obstacle almost arrested the great experiments he contemplated. He heard that the promises made to him were vanishing away, the necessary credit having been refused for the building of the new laboratory. And this, Pasteur sadly reflected, when millions and millions of francs were being spent on the Opera house! Wounded in his feelings, both as a scientist and a patriot, he prepared for the _Moniteur_, then the official paper, an article destined to shake the culpable indifference of public authorities. “...The boldest conceptions,” he wrote, “the most legitimate speculations can be embodied but from the day when they are consecrated by observation and experiment. Laboratories and discoveries are correlative terms; if you suppress laboratories, Physical Science will become stricken with barrenness and death; it will become mere powerless information instead of a science of progress and futurity; give it back its laboratories, and life, fecundity and power will reappear. Away from their laboratories, physicists and chemists are but disarmed soldiers on a battlefield. “The deduction from these principles is evident: if the conquests useful to humanity touch your heart--if you remain confounded before the marvels of electric telegraphy, of anæsthesia, of the daguerreotype and many other admirable discoveries--if you are jealous of the share your country may boast in these wonders--then, I implore you, take some interest in those sacred dwellings meaningly described as _laboratories_. Ask that they may be multiplied and completed. They are the temples of the future, of riches and of comfort. There humanity grows greater, better, stronger; there she can learn to read the works of Nature, works of progress and universal harmony, while humanity’s own works are too often those of barbarism, of fanaticism and of destruction.