Pasteur, Louis, 1822-1895; Scientists -- France -- Biography
“It is doubly regrettable,” he concluded, “that I should not have known
charbon already last year, for, on the one hand, I might have diagnosed
the redoubtable complication presented by the case, and, on the other
hand, sought for the mode of contamination, which at present escapes me
almost completely.” All he had been able to find was that the woman, a
charwoman, lived in a little room near a stable belonging to a horse
dealer. Many animals came there; the stable might have contained
diseased ones; M. Feltz had been unable to ascertain the fact. “I must
end,” he added, “with thanks to M. Pasteur for the great kindness he has
shown me during my intercourse with him. Thanks to him, I was able to
convince myself of the identity between the bacillus anthracis and the
bacteridium found in the blood of a woman who presented all the symptoms
of grave puerperal fever.”
At the time when that convincing episode was taking place, other
experiments equally precise were being undertaken concerning splenic
fever. The question was to discover whether it would be possible to find
germs of charbon in the earth of the fields which had been contaminated
purposely, fourteen months before, by pouring culture liquids over it.
It seemed beyond all probability that those germs might be withdrawn and
isolated from the innumerable other microbes contained in the soil. It
was done, however; 500 grammes of earth were mixed with water, and
infinitesimal particles of it isolated. The spore of the bacillus
anthracis resists a temperature of 80° C. or 90° C., which would kill
any other microbe; those particles of earth were accordingly raised to
that degree of heat and then injected into some guinea-pigs, several of
which died of splenic fever. It was therefore evident that flocks were
exposed to infection merely by grazing over certain fields in that land
of the Beauce. For it was sufficient that some infected blood should
have remained on the ground, for germs of bacteridia to be found there,
perhaps years later. How often was such blood spilt as a dead animal was
being taken to the knacker’s yard or buried on the spot! Millions of
bacteridia, thus scattered on and below the surface of the soil,
produced their spores, seeds of death ready to germinate.
And yet negative facts were being opposed to these positive facts, and
the theory of spontaneity invoked! “It is with deep sorrow,” said
Pasteur at the Académie de Médecine on November 11, 1873, “that I so
frequently find myself obliged to answer thoughtless contradiction; it
also grieves me much to see that the medical Press speaks of these
discussions in apparent ignorance of the true principles of experimental
method....
Public-domain text, read in full here on John Shaqi.
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