The last words of Buddha to the assembled Bickus are designed to remind them of the great and vital principle he has endeavoured to inculcate in their minds during the forty-five years of his preaching, viz., that change and mutability are acting upon all that exists, and are inherent in all parts of nature. This world, therefore, offering but an endless vicissitude of forms, that appear and disappear, has no real existence. It is an illusion from beginning to end. As long as man remains tied up, so to speak, to nature, he is carried away by the ever-acting principle of change: nowhere can he find any rest or fixity; he quits one existence to pass into another; he leaves one form to assume a different one. What happens to man befalls all other parts of nature. From this notion, Buddha infers that there is nothing existing but _name_ and _form_. There is no substance in nature, and therefore no reality. So much stress was laid by Buddha on this capital principle that he bequeathed it, as his last Will, to his disciples: he wished that they should ever bear in their minds and remember that he came among them for the purpose of making them thoroughly acquainted with it. From this cardinal point he inferred the chief conclusions that form his religious system, viz., metempsychosis, the contempt of the world, and Neibban. By the law of endless changes, man is hurried from one state into another, or from one form of being into another form. Where is the wise man that could love a world, or an existence therein, when he finds no substance, no reality in it? Is he not induced, or rather compelled, to search after a state in which he can find fixity, reality, and truth, or at least an exemption from the harassing condition of perpetual migration from one state into another?