While it is quite possible that some of the so-called toad-stones may really have been concretions found in the head of the toad, by far the greater part were probably small pebbles sold as “toad-stones” to those who believed in the magic virtues of such a stone and were ready to pay a good price for one. Where there is a demand there will always be a supply, and the rarer the genuine article is, the greater is the incentive to imitation or substitution. In the case of some of these “toad-stones” set in rings to serve as amulets, the material has been found to be the fossil palatal tooth of the ray, a species of fish.[334] The small share of material prosperity that fell to the lot of wits and literary men in the England of the sixteenth century, even in the age of Elizabeth, induced Thomas Nash (1567–1601) to liken the fate of the wit to that of the toad-stone, or, as he writes, of “the pearl,” which was said to be in the head of the toad, this “being of exceeding virtue, is enclosed with poison; the other, of no less value, compassed about with poverty.”[335] A writer of the same period affirms that if the toad-stone were touched to any part, “envenomed, hurt, or stung with rat, spider, wasp, or any other venomous beast,” the swelling and pain were diminished.[336] The bones of the lizard were supposed to have medicinal virtues similar to those attributed to various “stones” found in animals. The following directions are given by Encelius for securing these bones: “Put a green lizard, while still alive, in a closed vessel filled with the best quality of salt. In a few days the salt will have consumed the flesh and the intestines, and you can easily gather up the bones.”[337] These were used as remedies for epilepsy and were considered to be as efficacious as the hoofs of the elk, a recommendation which seems to have been regarded as sufficient to convince the most sceptical of the remedial virtues of the lizard’s bones. The crab furnished the stone called the crab’s-eye, because in form it resembled an eye. Like almost all the animal concretions, it was principally used as a remedy for those suffering from vesical calculi, and no other concretion was believed to be so efficacious in breaking up or dissolving the calculi in the case of those who had long been afflicted with them. Those referred to by Encelius were from the crawfish and are often used as eye-stones.[338] In the last joint of a crab’s claw was sometimes found a small concretion closely resembling in size and appearance a grain of millet-seed; it was in no wise like the “lapillus” found in crab’s eyes. We have the testimony of Cardanus that he had preserved two such concretions, one of which he had himself come across, while the other had been found by a colleague. They were smooth and light, and of a reddish-white color. Because they were very rarely met with, the circumstance was regarded as of good augury for the finder.[339]