"Runge in 1855 was the first to describe the formation of periodic chemical precipitates. He used blotting paper as the medium in which various chemical substances met by diffusion. In this way he studied the mutual reactions of solutions of ferrocyanide of potash, chloride of iron, and the sulphates of copper, iron, manganese, and zinc. The coloured precipitates appeared at different positions in the paper, and disappeared periodically at greater or longer intervals. The designs formed by these coloured precipitates change with the concentration of the saline solutions, or on the addition of oxalic acid, salts of potash or ammonia, and other substances. These designs are shown in a number of beautiful illustrations which accompany the work. In this {119} case the capillarity of the paper necessarily exerts a certain influence on the formation of the figures, but in addition to this, Runge admits the intervention of another force hitherto unknown, which he calls 'Bildungstrieb,' the formative impulse, which he considers to be the elementary vital force in the formation of plants and animals. "In 1867, R. Boettger obtained arborescent forms and ramifications of metallic vegetation by sowing fragments the size of a pea of crystals of the iron chlorides, chloride of cobalt, sulphate of manganese, nitrate and chloride of copper, etc., in an aqueous solution of silicate of sodium of specific gravity 1.18. These forms are due, as I shall show later on, to the surface tension of the oily precipitate; Boettger gives no explanation of the phenomenon. "To this force, viz. that of surface tension, is also due the cellular forms obtained by Traube in 1866. These were obtained from gelatine and tannin, from acetate of copper or lead, and from nitrate of mercury in an aqueous solution of ferrocyanide of potassium. These cells and precipitated membranes have also been studied by Reinke, F. Cohn, H. de Vries, and myself, who all observed the regression of these membranes, which although colloidal at the beginning of the reaction speedily become friable. This entirely refutes the opinion of Traube as to the constitution of the precipitated membranes. He supposed them to consist of masses of solid substance, with smaller orifices which do not permit the passage of the membranogenous substance, whilst the larger orifices through which it can pass are soon closed by the precipitate, the membrane itself thus growing by a process of intussusception. "Later on Traube himself considered the precipitated membrane to be a thin, solid gelatinous layer in which the water was mechanically entangled.