Peckolt and Geuther isolated from the bark the glucoside, _agoniadin_ (C_10_H_14_O_6_), which crystallizes in silky crystals fusible at 155°, slightly soluble in water, alcohol, bisulphuret of carbon, ether and benzine; soluble in nitric or sulphuric acids. In solution it is a golden yellow soon changing to green. Boiled in a dilute acid it splits into glucose and an undetermined substance. Oudeman obtained _plumieric_ acid (C_10_H_10_O_5_) from the milky juice deprived of its resin; the acid exists as microscopic, needle-like crystals, soluble in boiling water, alcohol and ether. It melts and decomposes at 130°. Botanical Description.--A tree, 12-18° high, commonly cultivated for ornament, well known in the islands, almost constantly bearing fragrant flowers, but rarely bearing fruit. Branches forked and peculiarly stumpy at the ends. Leaves alternate, broad lanceolate, entire, glabrous, the apices curved downward. Petioles short. Flowers creamy white, light yellow in the throat. Calyx 5-toothed. Corolla twisted, funnel-form, 5-lobed. Stamens 5, hidden in depths of the tube. Anthers dart- or arrow-formed. Style very short, thickened above. Stigma 2-parted. Two horizontal, cylindrical and long follicles joined at their bases, with numerous seeds in hollow receptacles, each seed encircled by a wing. _Alstonia scholaris_, Br. (_Echites scholaris_, L. and Blanco.) Nom. Vulg.--_Dita_, Tag.; _Dallopawen_, Iloc.; _Dita_ or _Alstonia Tree_, Eng. Uses.--The trunk bark is a febrifuge of great importance; it is official in the Pharmacopoeia of India and is widely used in the Philippines. Personally I have had occasion to use it in several cases of malarial fever in the town of San Mateo near Manila. It is astringent, anthelmintic and antiperiodic, highly useful in chronic diarrhoea and dysentery, not only for its astringent effects but for its tonic and restorative action. As a tonic it gives as good results as quinine. The dry powdered bark is given internally in wafers of 20-30 centigrams. The infusion is prepared from 15 grams of the dry comminuted bark to 300 of water. The dose is 30-60 grams 2 or 3 times a day. Another convenient preparation is the tincture, 75 grams of the powdered bark macerated 7 days in 500 grams of alcohol, shaking from time to time. It is then filtered and enough alcohol added to make up the 500 cc. The dose is 4-8 grams a day. I have often used the following wine as a tonic for convalescents and patients suffering from general debility: Finely powdered bark, 25 grams, muscatel or dry sherry one bottle; macerate a week, shaking every day, and filter; dose 1/2 wineglass with equal parts water a few minutes before each meal; children or very weak patients should take it after eating; it should always be diluted.