A staff of several highly trained and experienced biologists would be needed. The following organization is suggested as desirable, although, as indicated below, not necessarily essential in the beginning: (1) An expert especially interested in the problems of behavior, psychology, and sociology, with keen appreciation of practical as well as of theoretical problems; (2) an assistant trained especially in comparative physiology; (3) an expert in genetics and experimental zoology; (4) an assistant with training and interests in comparative anatomy, histology, and embryology; (5) an expert in experimental medicine, who could conduct and direct studies of the diseases of man as well as of the lower primates and of measures for their control; (6) an assistant trained especially in pathology and neurology. To this scientific staff of six highly trained individuals there should be added a business manager, a clerical force of three individuals, a skilled mechanician, a carpenter, and at least four laborers. The annual expenditures of an institute with such a working staff, would in southern California, approximate fifty thousand dollars. It would therefore be necessary that it have an endowment of approximately one million dollars. In the absence of this foundation it would, of course, be possible to make a reasonably satisfactory beginning on the work which has been outlined in the following less expensive manner. A working plant might be established, on ground rented or purchased at a low figure, for about ten thousand dollars; the salary of a director, assistants, a clerical helper, and combined mechanic and laborer might be estimated at the same figure; the cost of animals and of maintenance of the plant would approximate five thousand dollars. Thus, we should obtain as an estimate of the expenditures for the first year twenty-five thousand dollars. Without expansion, the work might be conducted during the second year for fifteen thousand dollars, and subsequently it might be curtailed or expanded, resources permitting, according as results achieved and in prospect justified.