Intervals, long, between doses, desirable, 77 Introduction, 1 Jennings’ studies of acidosis, 48 Kobert’s and Toth’s studies, 38 Law, Harrison, failure of, 96 makers, attitude to drug addiction, 102 What has it done for the addict? 102 Laws and old conceptions of drug addiction, 96 and their relations to narcotic drugs, 95 drug, enforcement and increased suffering of addicts, 96 Magendie’s findings, 38 Marme and oxydimorphine, 38 Mechanism, essential, of addiction disease, 41 of narcotic drug addiction disease, 36 of protection, 47 Medication, ignorant or unavoidable, and drug addiction, 27 opiate, indispensable and legitimate, 116 “specific,” fallacy of, 56 Misunderstanding of addict, cause of early failures in treatment, 5 “Narcotics,” definition of term, 114 Need, drug, minimum daily, 66 of the hour in study of drug addiction, 130 narcotic drug, and mental and muscular work, 69 Observation in Bellevue, sixteen months, day and night, 3 Observations on physical or body reaction, 32 Opiate, withdrawing, simply one stage, 92 Opiates, and their unique properties, 116 Organizations, medical duty of, 104 Origin of addiction, 25 Oxydimorphine and Marme theory, 38 Panaceas, search for, 56 Patients, intelligent, and the avoidance of complications, 78 People, eminent, and drug addiction, 27 Philanthropy and its opportunity, 135 Physician, average, is inexpert in handling addiction disease, 108 suffering from drug addiction, viewpoint of, 146 Physicians, honest, and their responsibility, 103 Pilocarpine, use of, 50 Practice, legitimate medical, 95 Practitioner, honest, and control of illicit drug traffic, 123 Principles, basic, of addiction-disease handling, 65 Problem, drug, still unsolved, 5 of drug addiction, ultimate solution of, 108 of the care of the innocent and worthy addict, 129 Profession, medical, attitude of, 50 Prostitution and “white-slavery,” 125 Protection, bodily, against opiate, 42 mechanism of, 47 Pulpit and press, duty of, 135 Purgation, excessive, warning against, 81 Purpose, chief, of most lay and medical workers, 96 Questions that confront the American people, 136 Reaction, normal, stage of, 29 to therapeutic and toxic doses, 29 of drug addicts to therapeutic agents, 68 Reduction, enforced, below bodily need, dangers of, 69 slow, 51 References to recent literature, 39 Regulation, legislative and administrative, 105 of intervals of narcotic drug administration, 66 “Relapses” and production of antidotal substance, 45 Report, 1915, of New York Dept. of Correction, 72 Preliminary, of Whitney Committee, 110 Responsibility for drug addiction laid on medical profession, 102 Restoration of drug addict to health, 83 Side, personal, of drug addiction, 137 Solution of drug problem, ultimate, 108