The narcotic drug problemBishop, Ernest S. (Ernest Simons)
Science
The narcotic drug problem
Bishop, Ernest S. (Ernest Simons)
Drug addiction
The subject of these tracings was a man well-known and prominent in his
community, 63 years of age, suffering from pneumonia with marked and
persisting cardiac and circulatory deficiency which did not respond to
the administration of the usual circulatory stimulants even in very
large doses. I was called in consultation. Found the patient very weak
and exhausted, with facial expression of protracted suffering and
anxiety and despondency. Morphine in usual therapeutic doses had been
daily administered for relief of pain, restlessness and sleeplessness,
being insufficient however to control those manifestations. Pulse
was, as shown in tracing number 1, very weak and intermittent. It
was impossible to account for the whole clinical picture and history
on the grounds of a typical pneumonia, present or resolving. Opiate
addiction was suspected and the patient questioned. He had been
suffering from opiate addiction-disease for many years, his addiction
developing unsuspected by him as a result of medication for a painful
and protracted condition many years previous. He begged to be allowed
to die without his wife and son being told of his affliction. The
following tracings made upon him are very instructive and significant,
and cannot be interpreted upon any grounds of psychical explanation of
addiction phenomena.
The last dose of morphine prior to these tracings was one-eighth of a
grain given at 3:30 P. M.
[Illustration: (Chart of Sphygmographic Tracings)]
First tracing (number 1) was made about 6:00 P. M.
Tracings 2, 3 and 4 were made at about fifteen minute intervals. They
were made following experimental hypodermic injections of morphine
sulphate to determine the extent of opiate need and organic dependence
upon opiate medication, and the amount of opiate required to restore
organic function and tone.
Tracing number 4, taking into consideration the asthenic and exhaustion
condition of the patient, shows full support to circulation with some
overaction.
Tracing number 5 was taken an hour or two after tracing number 4 to
determine the holding power of the dosage administered, after the
circulation had reacted from the immediate stimulation of the opiate
medication. This tracing, interpreted and considered together with the
clinical manifestations at the time, was decided to be about normal for
that patient at that time.
This patient would have died, not from pneumonia with cardiac
complications, but from insufficient control of the mechanism of opiate
addiction-disease.
On balanced and indicated daily morphine dosage, patient made very
rapid recovery and has continued well and active.
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