Early in 1778 Biddle again took the sea with the "Randolph," supported this time by four small vessels, fitted out by the South Carolina authorities. They were the "Gen. Moultrie," eighteen guns; the "Polly," sixteen; the "Notre Dame," sixteen; and the "Fair American," sixteen. With this force Capt. Biddle set out in search of a British squadron known to be cruising thereabouts, and probably the same vessels that had kept him a prisoner during so much of the previous year. On the 7th of March, 1778, the lookouts on the smaller vessels saw a signal thrown out from the masthead of the "Randolph," which announced a sail in sight. Chase was at once given; and by four o'clock she was near enough for the Americans to see that she was a large ship, and apparently a man-of-war. About eight o'clock the stranger was near enough the squadron for them to make out that she was a heavy frigate. The Englishman was not slow to suspect the character of the vessels with which he had fallen in, and firing a shot across the bows of the "Moultrie," demanded her name. "The 'Polly' of New York," was the response. Leaving the "Moultrie" unmolested, the stranger ranged up alongside the "Randolph," and ordered her to show her colors. This Biddle promptly did; and as the American flag went fluttering to the fore, the ports of the "Randolph" were thrown open, and a broadside poured into the hull of the Englishman. The stranger was not slow in replying, and the action became hot and deadly. Capt. Biddle was wounded in the thigh early in the battle. As he fell to the deck, his officers crowded about him, thinking that he was killed; but he encouraged them to return to their posts, and, ordering a chair to be placed on the quarter-deck, remained on deck, giving orders, and cheering on his men. It is said that Capt. Biddle was wounded by a shot from the "Moultrie," which flew wide of its intended mark. For twenty minutes the battle raged, and there was no sign of weakening on the part of either contestant. Suddenly the sound of the cannonade was deadened by a thunderous roar. The people on the other ships saw a huge column of fire and smoke rise where the "Randolph" had floated. The English vessel was thrown violently on her beam-ends. The sky was darkened with flying timbers and splinters, which fell heavily into the sea. The "Randolph" had blown up. A spark, a red-hot shot, some fiery object, had penetrated her magazine, and she was annihilated.