The nutrition of manChittenden, R. H. (Russell Henry)
Science
The nutrition of man
Chittenden, R. H. (Russell Henry)
Nutrition
A more striking illustration of the action of carbohydrate in sparing
proteid is seen in experiments on man, where the nitrogen intake is
reduced to a minimum, so as to constitute a condition of specific
nitrogen-hunger. In such a case, increasing amounts of carbohydrate
added to the intake reduce enormously the using up of tissue proteid.
The following experiment with a young man 22 years old and 71.3 kilos
body-weight, reported by Landergren,[29] affords good evidence of the
extent to which this proteid sparing power may manifest itself.
[29] Landergren: Untersuchungen über die Eiweissumsetzung des
Menschen, Skandinavisches Archiv für Physiologie, Band 14, p. 114.
We see here the nitrogen consumption fall to the exceedingly low level
of 3.34 grams per day, or 0.047 gram per kilo of body-weight. To
appreciate the full significance of this drop in the extent of proteid
metabolism, we may recall that Succi, with a body-weight of only 62.4
kilos, on the seventh day of fasting excreted 9.4 grams of nitrogen,
corresponding to a metabolism of 58.7 grams of tissue proteid. In
other words, with an intake of only 5.6 grams of proteid, the addition
of 908 grams of carbohydrate, with a total fuel value of 3745 calories,
reduced the consumption of tissue proteid to 20.8 grams. The same
individual, if fasting, would undoubtedly have used up at least 70
grams of tissue proteid.
+----+------------------------------------------++---------++------------+
| | Intake. || Output. || |
|Day.+--------+-----+--------+--------+---------++---------++ Proteid |
| |Proteid.| Fat.| Carbo- |Alcohol.|Calories.||Nitrogen ||metabolized.|
| | | |hydrate.| | ||of Urine.|| |
+----+--------+-----+--------+--------+---------++---------++------------+
| | grams |grams| grams | grams | || grams || grams |
| 1 | 35.2 | 6.1 | 507 | 26.6 | 2465.9 || 12.16 || 76.0 |
| 2 | 28.7 | 4.7 | 787 | 26.6 | 3574.3 || 8.37 || 52.3 |
| 3 | 28.8 | 4.7 | 841 | 26.6 | 3796.1 || 5.02 || 31.3 |
| 4 | 28.3 | 4.9 | 839 | 13.3 | 3690.5 || 4.50 || 28.1 |
| 5 | 5.4 | .. | 898 | .... | 3703.9 || 4.01 || 25.0 |
| 6 | 6.0 | .. | 931 | .... | 3841.7 || 3.36 || 21.0 |
| 7 | 5.6 | .. | 908 | .... | 3745.8 || 3.34 || 20.8 |
+----+--------+-----+--------+--------+---------++---------++------------+
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