My hopeful anticipations were, however, not realized. One day early in December Jensen reported to me that one of the finest animals had been attacked with the disease, and recommended that it should be shot, to prevent the disease spreading; and this was accordingly done. A few hours afterwards another one was seized in the same manner. The symptoms were at first those of great restlessness. The animal ran several times around the ship, first one way and then the other, with a vague uncertainty in its gait, and with an alternate raising and lowering of the head and tail, every movement indicative of great nervous excitement. After a while it started off toward the mouth of the harbor, barking all the while and seeming to be in mortal dread of some imaginary object from which it was endeavoring to fly. In a little while it came back, still more excited than before. These symptoms rapidly increased in violence, the eyes became bloodshot, froth ran from the mouth, and the dog became possessed of an apparently uncontrollable desire to snap at every thing which came in its way. The disease ran its course in a few hours. Weakness and prostration followed the excitement, and the poor animal staggered around the vessel, apparently unable to see its way, and finally fell over in a fit. After struggling for a little while in the snow, consciousness returned, and it got again upon its feet. Another fit followed soon afterward; and then they came one after another in rapid succession, until finally its misery was relieved by death, which occurred in less than twenty-four hours from the incipience of the attack. Meanwhile I had watched it closely, hoping to discover some clew to the cause, and to establish a cure. But I could obtain no light whatever. Dissection revealed nothing. There was no apparent inflammation either of the brain, the nerve centres, the spinal cord, or the nerves themselves; and I was wholly at a loss to understand the strange phenomenon. That it was not hydrophobia was shown by the fact that the animal rather desired than shunned water. Many of the symptoms attending that disease were, however, manifested; but it did not, like hydrophobia, appear to be communicated by the bite; for those dogs which happened to be bitten were not more speedily attacked than the others. [Sidenote: GREAT MORTALITY OF DOGS.] This case had scarcely reached its fatal termination before another was reported, and it was relieved of its misery by a bullet. Seven died during four days, and I saw with consternation my fine teams melting away and my hopes endangered; and while this was in progress I could only look on and wonder and experiment, but could never stop the contagion nor arrest the evil.