In the afternoon of Saturday, January 25th, 1868, Rev. G. W. Brush, of Delaware, a clergyman of estimable character and more than respectable talents, was found to have committed suicide. Sixteen or seventeen years previous to this fatal act, morphine had been prescribed to Mr. Brush for occasional disorder in the bowels and for a dormant cancer of the tongue. But something else which had not been prescribed--an unrelenting necessity to go on as he had begun--was also developed in his nature, which in time bore its matured and inevitable fruit. Mr. Brush made his case known for the first time to Dr. Barnes in November, 1866, when his habitual consumption of morphine varied from twelve to fifteen grains daily, with an occasional use of double this quantity. At this time, in the language of Dr. Barnes, he appeared greatly depressed, mourned over his life as a failure, and said he had been tempted to end it. He had once made a serious effort to abandon the habit, but the effect was so prostrating, and diarrhea, pouring like a flood, had borne him so near the gates of death, that he was compelled to resume the drug in order to save his life. But he was determined to make another attempt, and wished my professional services against the consequences which he well knew must follow. He entered upon the trial, reducing rapidly the amount of his morphine. I called on him in the course of two or three days, according to appointment, and found him wan and haggard, weak and almost wild with suffering. His hands, lips, and voice trembled. He tottered on his legs; and, though sweating profusely, he hovered about the fire to keep warm. Day followed day, while he still suffered and endured. On one occasion, as I entered, he had been writing, and read me his production. It was an account of the effects produced by morphine, the giving way of nerves, softening of the muscles, the depression, nightmare in the day-time, visions, horrid shapes; how the victim is sometimes engulfed in a flood of waters, while faces in all imaginary varieties of distortion, grin from the waves, and terrible eyes gleam forth from their depths. About this time, business which he thought could not be transacted in his suffering condition unexpectedly demanded his attention, and the attempt was abandoned.