antecedently to experience, to be suitable for the cure of disease, and “in accordance with the eternal fitness of things.” What, then, were the notions in obedience to which these marvellous remedies were ordained? If we exclude from present consideration all the really useful therapeutic agents, discovered doubtless by genuine experience and recorded by the ancient physicians, Galen and Hippocrates, Dioscorides and Avicenna, and all the rest, and also set aside those which, though not really useful, might have been readily mistaken for being so by imperfect early observation, we find the immense residue of absurd and monstrous recipes to fall into two categories; namely, the remedies which were exceedingly costly and the remedies which were either very painful or very disgusting. In other words, a large part of the medical science of all past ages proves that the doctors and their patients valued remedies _in proportion to the price to be paid for them_, either in money or in suffering. In short, they adopted freely the Doctrine of Sacrifice as applied to medicine. Considering that Nature nearly always proceeds on precisely the opposite track,--that she does not ask us “to do some great thing,” but, like the true prophet, only bids us “wash and be clean”; makes the cheapest and commonest things the most wholesome, and affords us normally, by our instinctive desire or loathing, the surest test of the fitness or unfitness of food for our use,--there is something exceedingly curious in the all but universal assumption of mankind that it was only necessary to find something particularly rare and expensive, or else something extraordinarily revolting, to obtain a panacea for all the woes of mortality. It was ridiculous (in the estimation of our forefathers) to suppose that a great noble or king should dissolve pearls in his drink or swallow liquid gold, and yet, forsooth, be no better after all than a poor wretch who could afford himself only a little milk or water. Still more incredible was it that a man should submit to some agonizing scarification or actual cautery, or should compel himself to bolt some inexpressibly disgusting mess which his doctor had taken a year to concoct and distil through a score of furnaces and retorts, and yet, when all was over, receive no more benefit than if he had endured no hardship, or had only drunk some cowslip julep or herb tea. Such tame and impotent conclusions could not be received for a moment. If patients would only _pay_ enough or _suffer_ enough, they _must_ be cured. This, it really seems, was the underlying conviction of men of old, on which half the therapeutics of past times were unconsciously based.