The Philosophy of Health; Volume 2 (of 2): or, an exposition of the physical and mental constitution of manSmith, Southwood
Science
The Philosophy of Health; Volume 2 (of 2): or, an exposition of the physical and mental constitution of man
Smith, Southwood
Hygiene; Physiology
817. The true nature of these poisonous exhalations is demonstrated by
direct experiment. If a quantity of the air in which they are diffused
be collected, the vapour may be condensed by cold and other agents, and
a residuum of vegetable or animal matter obtained, which is found to
be highly putrescent, constituting a deadly poison. A minute quantity
of this concentrated poison applied to an animal previously in sound
health, destroys life with the most intense symptoms of malignant
fever. If, for example, ten or twelve drops of a fluid containing
this highly putrid matter be injected into the jugular vein of a
dog, the animal is seized with acute fever; the action of the heart
is inordinately excited, the respiration is accelerated, the heat
increased, the prostration of strength extreme, the muscular power so
exhausted, that the animal lies on the ground wholly unable to stir or
to make the slightest effort; and, after a short time, it is actually
seized with the black vomit, identical, in the nature of the matter
evacuated with that which is thrown up by an individual labouring
under yellow fever. It is possible, by varying the intensity and the
dose of the poison thus obtained, to produce fever of almost any type,
endowed with almost any degree of mortal power. These facts, of which
practical applications of the highest utility are hereafter to be made,
may suffice to show the importance of the pulmonary membrane as an
absorbing surface. By the extent and energy of its absorbing power, it
is one of the great portals of life and health, or of disease and death.
818. The digestive surface is of much less extent than the pulmonary;
it is less vascular; it is further removed from the centre of the
circulating system, and it is covered with a thick mucus, which is
closely adherent to it; hence its absorbing power is neither so great
as that of the pulmonary membrane, nor do noxious substances in contact
with it affect the system so rapidly. An appreciable interval commonly
elapses between the introduction of a poison into the stomach and
its action upon the system. An emetic is commonly a quarter of an
hour before it begins to operate: arsenic itself is generally half an
hour, and sometimes three quarters of an hour, before it produces
any decided effect on the system: but at length a noxious substance,
applied to any part of the digestive membrane is introduced into the
circulating mass and produces its appropriate effects on the system,
just as when it is in contact with the pulmonary tissue.
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