986. It is then an ascertained fact, that there exists between the blood and the tissues a mutual reaction, not of a physical, but of a vital nature, in which the blood takes as active a part as the tissue, and the tissue as the blood; the blood exerting a vital attraction on the tissue, and the tissue on the blood. We only express this ultimate fact when we say (and this is all we can do) that in every part of the body, by virtue of a vital affinity, the tissue attracts from the blood the molecules of matter appropriate to its chemical composition, and the blood attracts from the tissue the particles which, having served their purpose there, are destined to other uses in the economy; or, if wholly useless, are absorbed into the current of the circulation to be expelled from the system. 987. We can see how the particles of matter which are attracted by the tissue from the blood are so deposited and disposed that the tissue always preserves its own shape, bulk, and relation to the surrounding tissues. This definite arrangement is the result of an action which has been already stated to be proper to the absorbent vessels. Previously to the deposition of a new particle of matter by a capillary, an old particle is removed by an absorbent, either a lymphatic or a vein. In removing the old matter, the absorbent forms a mould into which the capillary deposits the new molecules; and the form of every tissue and organ depends on the kind of mould formed for the reception of its nutrient matter by the absorbent vessel. The absorbents are thus the architects of the system; and the capillaries are both chemists which form the rough material employed in the structure, and masons which deposit and arrange it. The conjoint action of both sets of vessels is necessary to the formation of the simplest tissue; and it is by their united labour that the compound organs are built up out of the simple tissues. 988. It is conjectured that the immediate living agents by which this vital attraction is exerted between the blood and the tissues are the organic nerves. These nerves consist of two sets, those which enter as constituents into the tissues and those which accompany the capillaries. It has been shown (304), that while the membranous tunics of the capillaries diminish, the nervous filaments distributed to them increase; that the smaller and thinner the capillaries the greater the proportionate quantity of their nervous matter; and that this is most remarkably the case in organs of the greatest irritability. It is conceived that the capillaries, in consequence of the nervous structure which thus envelops them, exert upon the fluid which is flowing through them an influence perfectly analogous to that of the secreting organ, in consequence of which similar particles are abstracted from the blood as those which compose the tissue in which the operation takes place.