The constitution and temperament have much to do with the liability to disease and suffering during the change of life. Those of weak constitutions sometimes fail of the necessary stamina to carry them easily through the trials of this transition period. It has been remarked that the _lymphatic_ temperament is the most favorable to an easy change. Women with this temperament suffer less from nervous or bilious disorders, and quickly show signs of having been benefited by what has occurred. Those of a _sanguine_ temperament are more liable to floodings and to head symptoms; but such disorders with them usually readily yield to treatment. The _bilious_ temperament predisposes to disorders of the stomach and liver at this epoch; while the union of the nervous with the bilious temperament seems to predispose to mental diseases. The most suffering at this time of life is experienced by women of a _nervous_ temperament. The social position exerts an influence on the pain and the tendency to disease at this epoch. The poor who are forced to labor beyond their strength and who are exhausted by fatigue, anxiety, and want, suffer much. So also do those who have recently been exposed to some great sorrow. As the poet says:-- Danger, long travel, want, or woe, Soon change the form that best we know---- For deadly fear can time out-go, And blanch at once the hair. Hard toil can roughen form and face, And want can quell the eye's bright grace, Nor does old age a wrinkle trace More deeply than despair. The occupations of women also have an influence upon the change of life. Washerwomen are said in particular to suffer more than others on account of the exposure to which they are subject by their trade. Those who are confined many hours a day in close or damp rooms are unfavorably situated for passing through the various stages of the 'grand climacteric.' The rich, with plenty of time and means to care for themselves, often blindly or obstinately create an atmosphere about them and follow a mode of life, quite as deleterious as the enforced surroundings of their poorer sisters. DISEASES AND DISCOMFORTS.