2. _Atonic gout_, attended with debility of stomach or some other internal part, either with or without inflammation of the joints, accompanied with flying pains and considerable dyspepsia or indigestion. 3. _Retrocedent gout_, marked by inflammation of the joints, suddenly disappearing, and followed by immediate debility of the stomach or some other internal organ. 4. _Misplaced gout_, shown by inflammation of some internal part, preceded or not by some affection of the joints, which, however, quickly disappears. _General symptoms._—Dyspepsia, flatulence, lassitude, torpor, low spirits, cold and numbed extremities, with pricking and gnawing sensations in the part, cramps, turgescence of the veins of the foot and leg; the paroxysms usually coming on about two in the morning, with excruciating pains in the joint of the great toe, succeeded by shiverings, a sense of horror and general fever; the pain goes on increasing till the following evening, when it reaches its acme of suffering, from which time it gradually declines, a moisture breaks out on the body, and the patient begins to breathe in freedom, he falls into a tranquil sleep, and discovers on waking that the part so lately in torture is entirely free from pain, but swollen and inflamed. _Treatment._—In this disease the first indication is, to alleviate pain, which must be effected by giving an opiate of sufficient strength to effect that purpose, and at the same time, to shorten the paroxysm, exciting an action on the skin. To effect both these objects at once, doses of the following mixture should be taken every two hours till the desired result has been attained:— Take of Solution of Acetate of Ammonia 2 ounces. Spirits of Nitre 3 drachms. Antimonial Wine 2 drachms. Tincture of Squills 2 drachms. Laudanum 2 drachms. Camphor Water 3 ounces. Mix; two table-spoonfuls to be taken for a dose. The affected part is to be enveloped in soft wool or flannel, and the patient’s mind soothed; the limb kept at perfect rest, all exciting aliment discontinued, and where the patient is young, a low and abstemious dietary insisted on, and if necessary once or twice a week giving a mild purgative of magnesia and Epsom salts. When the paroxysms have been subdued, the colchicum, which some regard with so much favour, may be given either in half drachm doses of the wine or tincture, or in, what is better, the following formulary; but however taken, this drug should be always preceded by an aperient medicine. Take of Epsom Salts ½ ounce. Magnesia 2 drachms. Peppermint Water 6 ounces. Wine of Colchicum 3 drachms.