The _symptoms_ of tic-douloureux commence with a sudden plunging throbbing pain, darting as it were from over the eye, out of the cheekbone, under the orbit, or from the side of the lower jaw, and spreading, if the paroxysms are long continued, over the whole of one side of the face from forehead to chin. The pain is so abrupt, peculiar, and intense, as almost to deprive the sufferer of breath in its first assault. These shooting, throbbing, and as they are justly called, agonizing pains continue for an uncertain time, from only a few minutes to one or more hours in duration, subsiding either by degrees or by an instant cessation of pain, and ending as abruptly as the first shock began. Tic-douloureux is distinguished from tooth-ache by the situation, and from rheumatism, the only other affection it can be confounded with, by the peculiarity and violence of the pain, the shortness of its duration, by always coming on in paroxysms, and by the absence of all swelling and redness over the part. A peculiarity of this disease is, that though sometimes induced by the slightest touch of the finger, or the faintest breath of cold air, at another time the part may be slapped or rubbed with impunity. _Treatment._—This consists, in the first instance, acting on the digestive organs, correcting the functional disturbance, and lastly by elevating the tone of the system, and enabling it to restore the irritated nerves to a pristine soundness, or if this cannot be done by constitutional means, by the employment of _local_ remedies for that purpose. First, the best mode of acting on the digestive organs is by the steady employment of gentle aperients, care being taken to avoid any active or drastic purgative. For this purpose, a five grain compound rhubarb pill should be taken every night for several days till the bowels are brought into a healthy state, or a pill composed of equal parts of the compound rhubarb and colocynth pill may be substituted, where a little more active medicine is needed, the nightly dose being the same in this as the former. Secondly, to correct the functional disturbance, if, as most frequently, the result of indigestion, two table-spoonfuls of the following mixture are to be taken every four or six hours. Take of Hops 2 drachms. Cascarilla, bruised 1 drachm. Cloves, bruised 2 drachms. Infuse in a pint of boiling water for twelve hours; add Carbonate of Potass 2 drachms. Dissolve, and strain for use. Or where the stomach is cold and weak, as in advanced life, let the patient take a tea-spoonful of _Gregory’s powder_ in a little peppermint water twice or three times a day. Thirdly, to elevate the tone of the system, the body must be braced by tonics, which may be effected by either of the two following forms of medicine. Take of