When the attack is mild, the patient must be kept in the house, but need not be confined to bed. Very earnestly impress on the minds of your patients the baneful effects of opening the little watery blisters. An instance of this kind occurred in the writer’s vicinity, followed by the most lamentable and fatal results. The victim was a married woman, about 33 years of age; the blister appeared on the upper lip, and she, not knowing its nature, punctured it; inflammation, delirium, and death quickly succeeded each other, and baffled the skill of two medical men of long experience. There is another species of erysipelatous inflammation, which usually attacks the trunk of the body, and is vulgarly known as “Shingles.” It consists of a number of blisters extending round the waist. Little or no danger ever attends this species of erysipelas, but much pain is felt darting through the body; and these pains will continue to annoy the patient at times for some weeks after the eruption has disappeared. SMALL-POX. This, the most serious of all eruptive diseases, though having many symptoms in common with other affections of this inflammatory class, has some peculiar to itself, and which, carefully observed, will always accurately define the disease, and point out small-pox from every other analogous affection. These distinctive features are the _greater heat of the skin_, the _nausea_ and _sickness_ that from the first attend it, and the fact that the rash appears on the _fourth_ day of the illness, and not on the third, as in other eruptive diseases. Small-pox usually commences with shivering, pains in the back and head, heat, thirst, nausea, often sickness, a general feeling of languor and debility, quick full pulse, great heat and dryness of the skin, and a white furred tongue. This state continues with the usual febrile symptoms and nightly paroxysms till the fourth day, when a fine papillary rash, like grains of millet seed, breaks out on the face, neck, arms, and breast; in a few hours more extending over the rest of the body. On the fifth day the rash has become more distinct, each papilla has become larger and filled with a transparent fluid, changing its form into that of a vesicle, which, as the disease advances, enlarges with a _flat head_ and _depressed_ centre, the fluid passing from a transparent lymph into a yellowish matter. While this change is taking place, the extremities and the head swell, the head and face often becoming immensely distended, closing the eyes, and giving to the countenance a deformed and unnatural appearance. About the eighth day the maturation of the pustules is completed, and from thence to the eleventh day the declension of the eruption takes place, the pustules burst, the matter is effused, scabs are formed, and the dead cuticle begins, from the twelfth day, to peel off or disquamate, leaving pits in the skin, the consequence of the suppuration having destroyed the fatty matter beneath the cuticle.