=Symptoms and Course.=—There is a gray area surrounding the ulcer at first, also the floor is grayish in color. In this condition it is known as a =progressive= ulcer or a =foul= or =unclean= ulcer. This cloudiness or gray area may increase in size and the ulcer keep spreading, or it may go deeper even to perforation of the cornea. Some ulcers advance or spread on one side and heal on the opposite side so that they creep along on the cornea—these are the so-called =serpiginous ulcers=. With corneal ulcers there is irritation, pain, photophobia and increased lachrymation. There is usually some ciliary injection which is an indication of involvement of the iris and ciliary body. If iritis occurs there is contraction of the pupil with slow reaction. =Hypopyon= may develop. With iritis and the exudate there is likely to be adhesions between the iris and the lens known as posterior synechia. A few corneal ulcers are asthenic and do not have irritative symptoms and yet are dangerous. When the ulcer begins to heal it is called =retrogressive=. Dead tissue is cast off; other tissue becomes transparent from resorption. We have a =clean= ulcer. Symptoms disappear and cicatrization begins. Vessels extend to the ulcers and soon it is leveled up with the corneal surface. Cicatrization may leave it slightly below the corneal level or above it. If there should be perforation of the cornea from the ulcer there may be =complications=, e. g. keratocele, loss of aqueous, dislocation and expulsion of the lens, intra-ocular hemorrhage, flattening of the cornea, fistula of the cornea, glaucoma, intra-ocular suppuration, prolapse of the iris into the opening, etc. These complications and sequelæ that occur occasionally will not be considered here. After healing is complete by cicatrization there is opacity of the cornea in proportion to the depth and size of the ulcer. In months and years of time there is some clearing of the opacity so that small superficial opacities may become invisible. =Treatment of Corneal Ulcers.=—Most ulcers of the cornea are quite amenable to proper treatment and the prognosis is favorable. Neglect or wrong treatment is very dangerous. The treatment is local and constitutional. Often the ulcer is kept going by unwholesome constitutional conditions. =Local Treatment.=—This varies according to the stage of the ulcer, whether progressive or retrogressive. In a progressive or foul ulcer if due to trauma any foreign bodies should be removed. If the ulcer is a result of pathology of the conjunctiva it is of primary importance to treat the conjunctival condition. In mild cases of ulcer a dressing over the eye with atropine ½% to keep the pupil dilated is sufficient local treatment. The bandage protects the eye from bright light and other environment and the atropine puts the iris and ciliary body at rest preventing complications and giving nature her best chance to work.