W. A. Puckner, Secretary. COMMITTEE’S REPORT The following sweeping but rather indefinite claims are made for Iosaline. “Iosaline is a penetrator and overcomes the objectionable escharotic properties of Iodine; it is readily absorbed and may be used without discomfort or discoloration.” “The strong analgesic properties of Iosaline make it especially useful in controlling pain in cases of Neuralgia, Rheumatism, Gout, and Arthritis Deformans.” As there are few, if any, known iodin compounds which are “readily absorbed” through the skin and which will not at the same time produce discoloration or discomfort, it was thought worth while to take up the examination of Iosaline. The results of this examination are reported by the Chemical Laboratory of the Association as follows: _Laboratory Report_:--Iosaline is advertised by the Iosaline Company of New York, as a remedy for the treatment by external application, of rheumatism, gout, neuralgia, pneumonia and numerous other diseases. Concerning its composition the following statements are made: “A transparent, non-staining gelatinoid of combined iodine with menthol and methyl salicylate. “Alcohol 070. per cent. “Chemical tests demonstrate the preparation to contain 5 per cent. of iodine.” The placing of a cipher before the percentage figure for alcohol, though perhaps accidental and not meant to mislead, might cause a hasty or careless reader to understand 7 per cent. or .07 per cent., instead of 70 per cent., as the proportion of alcohol present. The preparation examined was a very pale yellowish, translucent solid having a strong odor of methyl salicylate and a fainter odor of menthol. A package sold for 2 ounces contained 51.7 gm. Qualitative tests indicated the presence of alcohol, an iodid, menthol, methyl salicylate, potassium, sodium, combined fatty acids and a trace of glycerin. Thyroid extract was not found. Quantitative examination indicated the following approximate composition for Iosaline: Alcohol (by weight) 48.05 per cent. Menthol 2.07 per cent. Methyl salicylate 10.25 per cent. Potassium iodid (4.25 per cent. iodin) 5.55 per cent. Soap 12.68 per cent. Glycerin a trace Water and undetermined matter to make 100 per cent.