The following report was submitted to the Council on Pharmacy and Chemistry by the subcommittee which examined Labordine: _To the Council on Pharmacy and Chemistry_:--Your subcommittee presents the following report on Labordine, sold by the Labordine Pharmacal Co., St. Louis. Labordine is advertised to physicians as having the following composition: Apium Graveolens (true active principle) “Process-Laborde” 35-3/8 Gaultheria Fragrantissima (true active principle) “Process-Laborde” 25-1/8 Acete Amide-Phenyle 15-1/8 Quinina 1-1/8 Benzoyl-Sulphyonic-Imide 23-1/4 It is stated to be a “vegetable antipyretic”; that {“}it reduces temperature without heart depression,” and physicians are warned to “avoid acetanilid poisoning and danger from other coal-tar antipyretics.” [Illustration] While the “formula” and the statement just quoted are sufficient evidence of the fraudulent character of the product, yet an abstract of the reports of the chemists who analyzed it is given further to demonstrate its character. Taking the average of the reports of analyses, labordine contains: Acetanilid 37.9 Free salicylic acid 6.9 Quinin present Corn starch present Milk sugar 34.7 This report of analysis only makes apparent that Labordine is not what it is claimed to be. While it is claimed to contain 23-1/4 per cent. saccharin, this substance was not present, or mere traces only. While, in a disguised way, it is stated to contain 15-1/8 per cent. acetanilid, it contained nearly 40 per cent. It is recommended that Labordine be not approved and that this report be published. The recommendation of the subcommittee was adopted by the Council, and in accordance therewith the above report is published. W. A. Puckner, Secretary. COMMENTS A concrete illustration of some general principles previously laid down is furnished by a nostrum too unimportant to be of any value, save to “point a moral and adorn a tale.” About thirteen years ago Labordine was advertised under the name of Analgine-Labordine, “A purely vegetable product,” “a combination of the active principles of _Camellia Thea_, _Apium Graveolens_, saccharin and carbohydrates,” “Superior to Antipyrine, Phenacetine, Antifebrine, Acetanilid”--note the use of two names for the same thing--“or any of their imitations,” and “unexcelled by any coal-tar product or their compounds.” In 1894 the name was changed to Labordine, in order, as its owner stated, to prevent its being mistaken for a coal-tar product of similar name.