“Operative wounds, whether large or small, can be rendered thoroughly antiseptic by freely spraying them with Germiletum....” “... it may be given internally in many dyspepsias and in all zymotic diseases.... In such conditions Germiletum is the ideal internal antiseptic and disinfectant.” In the present advertising, no evidence whatever is offered for the value of Germiletum, the Dios Company contenting itself with unsupported claims and cant phrases such as “... the truth is only reached through a final appeal to intelligent practical experience.” In the old circulars only crude, uncritical and meaningless tests to establish the antiseptic value of Germiletum are reported and none whatever as to its germicidal action. In the advertising matter sent out some time ago, for instance, were given “Microscopical, Bacteriological and Chemical Tests, Comparing Germiletum with Carbolic Acid.” These tests have no value whatever, unless it be to show the worthlessness of the preparation. This is particularly true as regards a series of experiments on “Germiletum as a Preventive of Lactic Fermentation,” in which one part of Germiletum in thirty parts of milk did not prevent fermentation. Such effect as indicated is probably due to the formaldehyd present. The tests show the absurdity of using the preparation for internal and external purposes. The referee challenges the therapeutic claims on the basis that they are extravagant and unsubstantiated. (The Chemical Laboratory of the American Medical Association reports that the alkalinity of Germiletum corresponds approximately to a 1 per cent. borax solution.) Palpebrine According to the Dios Chemical Company, Palpebrine is “A Reliable External Ocular Antiseptic” having, it is said, the following composition: “... each fluid ounce contains 1/116 grain Sulphate of Morphia, 1/7 grain Sulphate of Zinc, 1/11 grain Bi-Chloride of Mercury, 5-3/8 grains Boric Acid, 3/4 grain Salicylic Acid.” The essential virtues ascribed to Palpebrine, according to its makers, are its harmlessness and its therapeutic efficiency due, presumably, to its complex composition: “Attention is called to the constituents of this formula, each one of which is used by ophthalmologists. Their combination in Palpebrine is such as to blend their action in a very happy manner. Palpebrine acts as an antiseptic, an irritant, an astringent, and a nerve tonic to the mucous membrane of the eye.” “Palpebrine is superior in its action to the remedies now in use. It contains all the constituents of Aqua Conradi ... But to these are added a number of other agents which will prove it to be of much greater value and give it a broader field for action.” In all external afflictions of the eye the free use of Palpebrine is suggested in such statements as: