The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
The composition claimed for Hydropsin brands it as an irrational
mixture in which potent drugs are combined with, and more or less
covered up by, others that are obsolete and inefficient. The name,
instead of indicating its composition, suggests diseases in which it
may be thoughtlessly and indiscriminately used. The claim that the
danger of toxic or cumulative action has been removed, if accepted by
physicians, tends to uncritical use with possible disastrous results.
Hydropsin is ineligible for New and Nonofficial Remedies because of
conflict with Rules 1, 2, 6, 8 and 10.--(_From The Journal A. M. A.,
Jan. 8, 1916._)
DIGITALYSATUM
Report of the Council on Pharmacy and Chemistry
The Council has adopted the following report and authorized its
publication.
W. A. Puckner, Secretary.
Digitalysatum is sold in the United States by Ernst Bischoff Company,
Inc., New York. The firm claims that it is a dialysate prepared from
the juice of freshly gathered digitalis, containing all the active
principles, and representing the fresh plant weight for weight. It is
said to be standardized physiologically and to contain 12 per cent.
alcohol. Sterisol-Digitalysatum, intended for injection, appears
to be the “dialysate” without alcohol, diluted with equal parts of
physiologic sodium chlorid solution. The Council some years ago found
both products ineligible for New and Nonofficial Remedies because
of unwarranted therapeutic claims. The preparations are still being
advertised to physicians under claims which imply superiority to all
other digitalis preparations. For instance:
“Digitalysatum is the diuretic _par excellence_ in cardiac
insufficiency ...”
“Digitalysatum as a diuretic and cardiac stimulant is in a class
by itself, being quick of action, uniform in strength, and well
tolerated.”
“Digitalysatum differs from other forms of digitalis in these
respects:... Digitalysatum is free from fat, resins and colloids,
and is therefore well-borne by sensitive patients--the young and
the feeble--and is quickly absorbed and eliminated....”
The Council has elsewhere[28] expressed the conviction that tincture
of digitalis produces the full therapeutic effects of digitalis; that,
when properly made, the tincture is as stable as any liquid preparation
of digitalis now available, and that attempts to enhance the reputation
of proprietary products by exaggerating the disadvantages of the
official preparation are to be deplored. No adequate evidence is
offered of the claimed superiority of action of Digitalysatum.
[28] Report on Proprietary Digitalis Preparations, J. A. M. A., Dec. 4,
1915, p. 2024.
By implication, the claim is made that Digitalysatum is superior to
other digitalis preparations in respect to toxicity:
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