The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
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The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
The use of an almost identical product (said, however, to contain
only 1/2 grain iodin to each fluidram) was described in 1908 by Dr.
Ingraham of Binghamton, N. Y., in “Five Years Successful Experience
with a Special Mode of Treating Pulmonary Tuberculosis.” In 1910 The
Journal[1] characterized the preparation as “one of the innumerable
‘treatments’ for pulmonary tuberculosis that have arisen, had their
day and, more or less gracefully, retired.” If the preparation had
value for the purpose for which it is recommended, its use during these
twelve years should have secured its general recognition. There is no
satisfactory evidence of its therapeutic efficacy. The Council refused
recognition to Bromin-Iodin Comp. and, after submitting this report to
the Bromin-Iodin Chemical Company, authorized its publication.--(_From
The Journal A. M. A., Dec. 23, 1916._)
AMMONIUM HYPOPHOSPHITE OMITTED FROM N. N. R.
Report of the Council on Pharmacy and Chemistry
Ammonium hypophosphite was admitted to New and Nonofficial Remedies
in 1908 as a preliminary step in the consideration of a preparation
containing it--“Gardner’s Syrup of Ammonium Hypophosphite”--because
the Council standardizes unofficial products before considering
preparations or mixtures of these.
The therapeutic use of hypophosphites being irrational (see, “The
Hypophosphite Fallacy,” Report of the Council on Pharmacy and
Chemistry, The Journal, Sept. 2, 1916, p. 760), the salt, ammonium
hypophosphite, deserves continued recognition only on condition that
this salt of ammonium is superior to other salts from which may be
obtained the effect of the ammonium radical. It has been claimed that
ammonium hypophosphite has a less objectionable taste than other
ammonium salts used for similar purposes. This claim would merit
serious consideration if in addition to being less objectionable to
the taste, the effects of ammonium hypophosphite were equal to or more
desirable than the official ammonium salts. There is no evidence that
this condition is met by the hypophosphite salt.
Ammonium hypophosphite has long been known, yet it is not official
in the Austrian, Belgian, British, French, German, Hungarian,
Italian, Swedish, Swiss or United States Pharmacopeias. Neither is it
mentioned in the leading textbooks on materia medica, pharmacology or
therapeutics. In short it appears to be an instance of an obscure and
superfluous salt selected for proprietary exploitation.
Since the continued recognition of ammonium hypophosphite would tend to
perpetuate the hypophosphite fallacy, and because there is no evidence
supporting its advantage as a means of securing the effect of ammonium
salts the Council directed its omission from New and Nonofficial
Remedies.--(_From Reports of Council on Pharmacy and Chemistry, 1916,
p. 51._)
ALPHOZONE OMITTED FROM N. N. R.
Report of the Council on Pharmacy and Chemistry
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